"The problem? The availability!"
Functional bioactive peptides and proteins have an enormous yet underutilised economic potential to improve the ecological balance in several major industry sectors producing or processing biological material, be it agriculture, food, pharma, or cosmetics.
The problem? The availability!
The Better Peptide Platform aims to change that substancially and is coming head strong after conventional solid-phase peptide synthesis as the gold standard in commercial peptide production and its desastrous ecological footprint, producing tons of hazardous organic solvent waste per year, its economically unviable cost of production, and its limitations to produce truly tailor-made complex peptides at industry-relevant scales.
Modular design of the carrier fusion protein allows for the production of both, linear and circular peptides. Only few conditions apply for circulation of peptides.
Forward-looking carrier fusion design combines all molecular tools to simplify downstream processing.
Ideal for peptides of 20-150 amino acid length, the Better Peptides Platform closes a critical gap between solid-phase peptide synthesis and recombinant protein expression.
Tailor-made Better Peptides are released from the carrier fusion protein without process-related modifications, scars or residual amino acids for native termini.
Utilizing host cell biology, Better Peptides are naturally protected from modifications, available in high yields, and of high purity with minimal downstream processing.
From milligrams of peptide candidates to multi-ton commerical stage peptide-based products, the range of production scale is virtually limitless.
The Better Peptides Platform requires no specialized chemicals (e.g. protected amino acids) and hazardous organic solvents (e.g. acetonitrile, DMF etc.).
Smart molecular engineering, readily available common renewable biological resources, no need for specialized equipment or chemicals, and economy of scale contribute to keep production costs low and offer new commericially viable opportunities.
"Bioeconomics provides a general, desirable, and worthwhile added benefit compared to conventional methods."
Badische Peptide und Proteine GmbH has won the Bioeconomy Innovation Award 2023 and was able to convince the attending entrepeneurs and bioscientists from a broad range of research fields of its strategical advantages for a future-oriented biobased peptide-industry build from renewable biological resources.
Figure | Bioeconomy Innovation Award 2023.